Dome-Type: A Distinctive Variant of Colonic Adenocarcinoma

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Dome-Type: A Distinctive Variant of Colonic Adenocarcinoma

Introduction. Ten cases of dome-type adenocarcinoma of the colon have been reported so far. Most of them were presented as early lesions, with endoscopic and microscopic distinguishing features. Methods and Results. A raised plaque was removed from the right colon during colonoscopy in a 56-year-old man. Histopathological examination showed a cancerized adenoma invading the submucosa with sever...

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Dome-type carcinoma of the colon; a rare variant of adenocarcinoma resembling a submucosal tumor: a case report

BACKGROUND Dome-type carcinoma (DC) is a distinct variant of colorectal adenocarcinoma and less than 10 cases have been described in the literature. Most of the previously reported cases were early lesions and no endoscopic observations have been described so far. We herein report a case of a DC invading the subserosal layer, including endoscopic findings. CASE PRESENTATION A highly elevated ...

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Clear cell adenocarcinoma of the colon arising in endometriosis: a rare variant of primary colonic adenocarcinoma.

Colonic adenocarcinomas composed predominantly or exclusively of cells with clear cytoplasm are extremely rare. 1 2 Considerable diagnostic diYculties can arise in distinguishing primary colonic clear cell adenocarci-noma and metastatic carcinoma from sites such as ovary or kidney. Here, we describe a case of primary colonic clear cell adenocarci-noma that probably arose in endometriosis. The p...

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Dome formation by a human colonic adenocarcinoma cell line (HCA-7).

A new cell line, HCA-7, has been established from a primary human colonic adenocarcinoma. The HCA-7 cells have an epithelial morphology by phase-contrast microscopy, they secrete carcinoembryonic antigen, and they form adenocarcinomas when injected s.c. into nude mice. HCA-7 cells retain some of the morphological and functional polarity exhibited by normal colonic epithelium. Cells form a polar...

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ژورنال

عنوان ژورنال: Case Reports in Pathology

سال: 2012

ISSN: 2090-6781,2090-679X

DOI: 10.1155/2012/284064